Bioactive ingredients from natural sources possess well-known positive effects in\ncosmetic applications. Among them, phenolic acids have emerged with very interesting potential.\nCaffeic acid (CAF) is one of the most promising active compounds because it possess antioxidant,\nanti-inflammatory, antitumoral and anti-wrinkle effects. In order to increase its local bioavailability\nin topical applications, the vehiculation of caffeic acid can lead to a new raw material of cosmetic\ninterest. For this purpose, clay minerals possess excellent properties, such as low or null toxicity\nand good biocompatibility. Clays are able to host a wide range of active ingredients in the interlayer\nregion, using a green process known as intercalation reaction. The hosting of cosmetic actives\ninto the layered structure of anionic clays allows the preparation of new materials with enhanced\nstability towards oxidation and photodegradation, better local bioavailability, and easier workability.\nIn this paper, the successful vehiculation of caffeic acid into anionic clay is presented. The obtained\nhybrid is very promising for the cosmetic market because of its higher bioavailability and prolonged\nantioxidant activity.
Loading....